Pneumonia is the second leading cause of death in Hong Kong. Streptococcus pneumoniae is a common bacterium that can cause pneumonia, lung infections, meningitis, otitis media, sepsis, and other severe diseases, sometimes resulting in death. According to the guidelines from the Hong Kong Centre for Health Protection, it is recommended that everyone aged 2 years and older, as well as seniors aged 65 and above who are at high risk, should receive the pneumococcal vaccine. Vaccination can prevent invasive infections and is widely recognized as one of the most effective measures. Vaccination Recommendations Age: Individuals aged 2 years and older should receive 1 dose. Note: There should be a gap of 1 year between the administration of the 23vPPV and Vaxneuvance 15 vaccines. Contraindications/Side Effects Individuals with a history of severe allergic reactions to any component of the vaccine or a previous dose of the 23-valent pneumococcal vaccine (Prevenar 23). Individuals under 18 years of age. Pregnant or breastfeeding individuals. Individuals with a fever at the time of their appointment should postpone vaccination until they have recovered.